apalutamide will lessen the level or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with drugs which are CYP3A4 substrates may end up in reduced exposure to those prescription drugs.Drug interactions may change how your medicines d… Read More